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Following two post-doctoral fellowships studying experimental biophysics at the Centre de Biochimie Structurale, in Montpellier, France, and at the National Institutes of Health, in Bethesda, MD, Dr. Matthew Ferguson joined the faculty of the Department of Physics at Boise State University in late 2013. He earned his doctorate in physics from the University of Maryland and his B.S. in physics & mathematics from Texas Christian University in Fort Worth. Dr. Ferguson's current research emphasis is in the area of fluorescence microscopy, specifically the development of dynamic in vivo single molecule imaging at or below the diffraction limit. He considers himself an experimentalist, and an underlying theme in his research has been the interface between dynamical systems and thermodynamics in both physical and biological systems and the combination of physics, computer simulation and multidimensional data analysis to interpret the results of his experiments in a straightforward way, turning information into knowledge about a physical or biological system.
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Collaborations and top research areas from the last five years
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ENG-BIOTECH: Collaborative Research: Data-driven Mechanomics to Uncover Age-related Mechanoregulation of Bone
Uzer, G. (PI), Ferguson, M. (CoPI), Satici, A. (CoPI) & Fitzpatrick, C. (CoPI)
1/02/25 → 31/01/28
Project: Research
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Equipment for Spatiotemporal Dynamics of the Genome by 3D Orbital Tracking
Ferguson, M. (PI)
National Institute of General Medical Sciences
1/05/17 → 31/07/25
Project: Research
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BPS2026 – Transcriptional activation and RNA regulatory kinetics in living cells studied by 3D orbital tracking fluorescence cross-correlation spectroscopy
Nisha, C. J., Roberts, J., Hayden, E. & Ferguson, M. L., Feb 2026, In: Biophysical Journal. 125, 4, p. 142a 1 p.Research output: Contribution to journal › Article › peer-review
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Data Storage in Cellular DNA: Contextualizing Diverse Encoding Schemes
Dagher, G. G., Machado, A. P., Davis, E. C., Green, T., Martin, J. & Ferguson, M., Jun 2021, In: Evolutionary Intelligence. 14, 2, p. 331-343 13 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Nuclear envelope mechanobiology: Linking the nuclear structure and function
Goelzer, M., Goelzer, J., Ferguson, M. L., Neu, C. P. & Uzer, G., Dec 2021, In: Nucleus. 12, 1, p. 90-114 25 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile21 Scopus citations7 Downloads (Pure) -
Nano-Resolution in Vivo 3D Orbital Tracking System to Study Cellular Dynamics and Bio-Molecular Processes
Coskun, U. C., Ferguson, M. L., Vallmitjana, A., Huynh, A., Goelzer, J., Sun, Y., Liao, S. C. J., Shah, S., Gratton, E. & Barbieri, B., 2020, Proceedings of SPIE. Gregor, I., Koberling, F. & Erdmann, R. (eds.). 1124614. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 11246).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review
2 Scopus citations -
A Study of Transcriptional Activation by the Transcription Factor Gal4 in Saccharomyces cerevisiae by 3D Orbital Tracking and in vivo RNA Labelling
Torres, I., Figueroa, A., Pool, M. & Ferguson, M. L., 12 Jul 2019.Research output: Contribution to conference › Presentation