A thermally-stable enzyme detection assay that amplifies signal autonomously in water without assistance from biological reagents

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

This Communication describes a thermally-stable small molecule and a corresponding assay strategy that autonomously amplifies a colorimetric signal when a specific enzyme biomarker is detected.

Original languageEnglish
Pages (from-to)394-396
Number of pages3
JournalChemical Communications
Volume49
Issue number4
DOIs
StatePublished - 14 Jan 2013

Keywords

  • Benzoquinones/chemistry
  • Biological Assay/methods
  • Catalase/chemistry
  • Colorimetry
  • Drug Stability
  • Galactosidases/chemistry
  • Hot Temperature
  • Indicators and Reagents/chemistry
  • Signal Processing, Computer-Assisted
  • Water/chemistry

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