@inproceedings{d47cef21c060459d9de10d1e7f24f688,
title = "Absent sequences: Nullomers and primes",
abstract = "We describe a new publicly available algorithm for identifying absent sequences, and demonstrate its use by listing the smallest oligomers not found in the human genome (human nullomers), and those not found in any reported genome or GenBank sequence (primes). These absent sequences define the maximum set of potentially lethal oligomers. They also provide a rational basis for choosing artificial DNA sequences for molecular barcodes, show promise for species identification and environmental characterization based on absence, and identify potential targets for therapeutic intervention and suicide markers.",
keywords = "Algorithms, Base Sequence, Computational Biology, DNA/genetics, Databases, Genetic, Genome, Human, Humans, Sequence Analysis/statistics \& numerical data, Sequence Analysis, DNA/statistics \& numerical data, Software",
author = "Greg Hampikian and Tim Andersen",
year = "2007",
doi = "10.1142/9789812772435\_0034",
language = "English",
isbn = "9812704175",
series = "Pacific Symposium on Biocomputing 2007, PSB 2007",
pages = "355--366",
booktitle = "Pacific Symposium on Biocomputing 2007, PSB 2007",
note = "Pacific Symposium on Biocomputing, PSB 2007 ; Conference date: 03-01-2007 Through 07-01-2007",
}
