An Algorithm for Partial Functional Differential Equations Modeling Tumor Growth

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Abstract

We introduce a parallel algorithm for the numerical simulation of the growth of human tumor cells in time-varying environments and their response to therapy. The behavior of the cell populations is described by a system of delay partial differential equations with time-dependent coefficients. We construct the new algorithm by developing a time-splitting technique in which the entire problem is split into independent tasks assigned to arbitrary numbers of processors chosen in light of available resources. We present the results of a series of numerical experiments, which confirm the efficiency of the algorithm and exhibit a substantial decrease in computational time thus providing an effective means for fast clinical, case-by-case applications of tumor invasion simulations and possible treatment.

Original languageAmerican English
Pages (from-to)85-92
Number of pages8
JournalApplied Mathematics and Computation
Volume321
DOIs
StatePublished - 15 Mar 2018

Keywords

  • Cancer dynamics
  • Cell population
  • Parallel algorithm
  • Tumor growth

EGS Disciplines

  • Mathematics

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