TY - JOUR
T1 - Bgp, a secreted glycosaminoglycan-binding protein of Borrelia burgdorferi strain N40, displays nucleosidase activity and is not essential for infection of immunodeficient mice
AU - Parveen, Nikhat
AU - Cornell, Kenneth A.
AU - Bono, James L.
AU - Chamberland, Christen
AU - Rosa, Patricia
AU - Leong, John M.
PY - 2006/5
Y1 - 2006/5
N2 - Bgp, one of the surface-localized glycosaminoglycan-binding proteins of the Lyme disease spirochete, Borrelia burgdorferi, exhibited nucleosidase activity. Infection of SCID mice with B. burgdorferi strain N40 mutants harboring a targeted insertion in bgp and apparently retaining all endogenous plasmids revealed that Bgp is not essential for colonization of immunocompromised mice.
AB - Bgp, one of the surface-localized glycosaminoglycan-binding proteins of the Lyme disease spirochete, Borrelia burgdorferi, exhibited nucleosidase activity. Infection of SCID mice with B. burgdorferi strain N40 mutants harboring a targeted insertion in bgp and apparently retaining all endogenous plasmids revealed that Bgp is not essential for colonization of immunocompromised mice.
UR - http://www.scopus.com/inward/record.url?scp=33646344197&partnerID=8YFLogxK
U2 - 10.1128/IAI.74.5.3016-3020.2006
DO - 10.1128/IAI.74.5.3016-3020.2006
M3 - Article
C2 - 16622242
AN - SCOPUS:33646344197
SN - 0019-9567
VL - 74
SP - 3016
EP - 3020
JO - Infection and Immunity
JF - Infection and Immunity
IS - 5
ER -
