TY - JOUR
T1 - Caffeine effects
T2 - Interaction of drug and wheelrunning experience
AU - Meliska, Charles J.
AU - Eric Landrum, R.
AU - Wing Hong Loke, Hong Loke
PY - 1985/10
Y1 - 1985/10
N2 - Male Sprague-Dawley rats were tested for wheelrunning following repeated injections of caffeine or distilled water after varying amounts of experience with caffeine and wheelrunning. Rats experienced with caffeine in combination with wheelrunning ran significantly more than rats experienced only with caffeine or wheelrunning alone. Results suggest that caffeine's stimulant effects are greater when subjects are experienced with wheelrunning while under the influence of the drug.
AB - Male Sprague-Dawley rats were tested for wheelrunning following repeated injections of caffeine or distilled water after varying amounts of experience with caffeine and wheelrunning. Rats experienced with caffeine in combination with wheelrunning ran significantly more than rats experienced only with caffeine or wheelrunning alone. Results suggest that caffeine's stimulant effects are greater when subjects are experienced with wheelrunning while under the influence of the drug.
KW - Behavioral tolerance
KW - Caffeine
KW - Drug experience
KW - Wheelrunning
UR - http://www.scopus.com/inward/record.url?scp=0022377196&partnerID=8YFLogxK
U2 - 10.1016/0091-3057(85)90429-0
DO - 10.1016/0091-3057(85)90429-0
M3 - Article
C2 - 4070339
AN - SCOPUS:0022377196
SN - 0091-3057
VL - 23
SP - 633
EP - 635
JO - Pharmacology, Biochemistry and Behavior
JF - Pharmacology, Biochemistry and Behavior
IS - 4
ER -