Abstract
Male Sprague-Dawley rats were tested for wheelrunning following repeated injections of caffeine or distilled water after varying amounts of experience with caffeine and wheelrunning. Rats experienced with caffeine in combination with wheelrunning ran significantly more than rats experienced only with caffeine or wheelrunning alone. Results suggest that caffeine's stimulant effects are greater when subjects are experienced with wheelrunning while under the influence of the drug.
| Original language | English |
|---|---|
| Pages (from-to) | 633-635 |
| Number of pages | 3 |
| Journal | Pharmacology, Biochemistry and Behavior |
| Volume | 23 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 1985 |
Keywords
- Behavioral tolerance
- Caffeine
- Drug experience
- Wheelrunning
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