Carrier Protein Mediated Cargo Sensing in Quorum Signal Synthases

Patrick D. Fischer, Abu Sayeed Chowdhury, Thomas Bartholow, Shibani Basu, Eric Baggs, Huel S. Cox, Srđan Matošin, Michael D. Burkart, Lisa Warner, Rajesh Nagarajan, Haribabu Arthanari

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Acyl-homoserine lactone synthases make specific AHL quorum sensing signals to aid virulence in Gram-negative bacteria. Here, we use solution NMR spectroscopy to demonstrate that the carrier protein–enzyme interface accurately reveals substrate recognition mechanisms in two quorum signal synthases.

Original languageAmerican English
Pages (from-to)1014-1017
Number of pages4
JournalChemical Communications
Volume59
Issue number8
DOIs
StatePublished - 25 Jan 2023

EGS Disciplines

  • Chemistry

Fingerprint

Dive into the research topics of 'Carrier Protein Mediated Cargo Sensing in Quorum Signal Synthases'. Together they form a unique fingerprint.

Cite this