Collagen fibrillogenesis on Ti-6Al-4V-ELI

Michelle Gerritsen, Janet M. Hampikian, William B. Knowlton, Julia Thorn Oxford, L. R. Warner, David Araujo, Zak Clark

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Collagen is a critical emerging biomaterial for use in drug delivery, for scaffolding for tissue regeneration, and for surgical purposes. This is due to its low antigenicity, as well as the fact that collagen is biodegradable and absorbable. This paper describes preliminary work on the deposition of fibronectin, type I collagen, and the globular domain of collagen type V/XI (V0) on Ti6Al4VELI via adsorption. Characterization of the early stages of fibrillogenesis via optical microscopy and atomic force microscopy are presented. Atomic force microscopy indicates that fibronectin was deposited; however, the deposition of the type I collagen and VO was not confirmed.

Original languageEnglish
Title of host publicationMaterials Science and Technology 2005 - Proceedings of the Conference
Pages97-100
Number of pages4
StatePublished - 2005
EventMaterials Science and Technology 2005 Conference - Pittsburgh, PA, United States
Duration: 25 Sep 200528 Sep 2005

Publication series

NameMaterials Science and Technology
Volume1
ISSN (Print)1546-2498

Conference

ConferenceMaterials Science and Technology 2005 Conference
Country/TerritoryUnited States
CityPittsburgh, PA
Period25/09/0528/09/05

Keywords

  • Atomic force microscopy
  • Biocompatibility
  • Collagen
  • Fibronectin
  • Titanium

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