@inproceedings{eb0c966e43784d55b3c91f51d6ef76be,
title = "Computational evaluation of planarian regeneration models",
abstract = "We have combined a cell-based modeling platform with a database of formally encoded morphological experiments and their outcomes in order to automate the search for computational models of cellular networks involved in maintenance of morphology and to validate such models against existing experimental outcomes. To achieve automated validation of virtual cellular models, we have developed an algorithm for converting a formal graph representation of planarian morphologies into a polygon representation which can be overlayed with a cell-based model. We show how the overlay algorithm can be used as a basis for the fitness function to guide automated searches for models of cellular development.",
keywords = "Planaria, Regeneration, Tissue modeling",
author = "Marianna Budnikova and Habig, {Jeffrey W.} and Tim Andersen",
note = "Publisher Copyright: {\textcopyright}2014 International Conference on Artificial Intelligence, ICAI 2014 - WORLDCOMP 2014.All right reserved.; 2014 International Conference on Artificial Intelligence, ICAI 2014 - WORLDCOMP 2014 ; Conference date: 21-07-2014 Through 24-07-2014",
year = "2014",
language = "English",
series = "Proceedings of the 2014 International Conference on Artificial Intelligence, ICAI 2014 - WORLDCOMP 2014",
pages = "555--560",
editor = "Arabnia, {Hamid R.} and {de la Fuente}, David and Kozerenko, {Elena B.} and LaMonica, {Peter M.} and Liuzzi, {Raymond A.} and Olivas, {Jose A.} and Todd Waskiewicz and George Jandieri and Solo, {Ashu M.G.} and Tinetti, {Fernando G.}",
booktitle = "Proceedings of the 2014 International Conference on Artificial Intelligence, ICAI 2014 - WORLDCOMP 2014",
}