Design of small molecule reagents that enable signal amplification via an autocatalytic, base-mediated cascade elimination reaction

Hemakesh Mohapatra, Kyle M. Schmid, Scott T. Phillips

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

This Communication describes three small molecule reagents that amplify the signal for a detection event via an autocatalytic reaction. Two signals are obtained from each reagent: (i) the dibenzofulvene chromophore and (ii) piperidine, which can be visualized using a pH indicator dye. The reagents are demonstrated in a model assay for palladium.

Original languageEnglish
Pages (from-to)3018-3020
Number of pages3
JournalChemical Communications
Volume48
Issue number24
DOIs
StatePublished - 22 Feb 2012

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