DNA fuel for free-running nanomachines

A. J. Turbefield; J. C. Mitchell; B. Yurke; A. P. Mills; M. I. Blakey; F. C. Simmel

DNA fuel for free-running nanomachines

A. J. Turbefield
, J. C. Mitchell
, B. Yurke
, A. P. Mills
, M. I. Blakey
, F. C. Simmel

Research output: Contribution to journal › Article › peer-review

322 Scopus citations

Abstract

We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.

Original language	English
Pages (from-to)	118102
Journal	Physical Review Letters
Volume	90
Issue number	11
State	Published - 21 Mar 2003
Externally published	Yes

Keywords

Base Sequence
DNA/chemistry
Kinetics
Nanotechnology/methods
Nucleic Acid Conformation
Nucleic Acid Hybridization
Oligonucleotides/chemistry

Cite this

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title = "DNA fuel for free-running nanomachines",

abstract = "We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.",

keywords = "Base Sequence, DNA/chemistry, Kinetics, Nanotechnology/methods, Nucleic Acid Conformation, Nucleic Acid Hybridization, Oligonucleotides/chemistry",

author = "Turbefield, \{A. J.\} and Mitchell, \{J. C.\} and B. Yurke and Mills, \{A. P.\} and Blakey, \{M. I.\} and Simmel, \{F. C.\}",

year = "2003",

month = mar,

day = "21",

language = "English",

volume = "90",

pages = "118102",

number = "11",

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TY - JOUR

T1 - DNA fuel for free-running nanomachines

AU - Turbefield, A. J.

AU - Mitchell, J. C.

AU - Yurke, B.

AU - Mills, A. P.

AU - Blakey, M. I.

AU - Simmel, F. C.

PY - 2003/3/21

Y1 - 2003/3/21

N2 - We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.

AB - We describe kinetic control of DNA hybridization: loop complexes are used to inhibit the hybridization of complementary oligonucleotides; rationally designed DNA catalysts are shown to be effective in promoting their hybridization. This is the basis of a strategy for using DNA as a fuel to drive free-running artificial molecular machines.

KW - Base Sequence

KW - DNA/chemistry

KW - Kinetics

KW - Nanotechnology/methods

KW - Nucleic Acid Conformation

KW - Nucleic Acid Hybridization

KW - Oligonucleotides/chemistry

UR - https://www.scopus.com/pages/publications/0038528527

M3 - Article

C2 - 12688969

AN - SCOPUS:0038528527

SN - 0031-9007

VL - 90

SP - 118102

JO - Physical Review Letters

JF - Physical Review Letters

IS - 11

ER -

DNA fuel for free-running nanomachines

Abstract

Keywords

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