Editorial: Gut microbiota and gastrointestinal disorders, volume II

The human gut microbiota, an intricate ecosystem of bacteria, viruses, fungi, and archaea, plays a pivotal role in maintaining gastrointestinal (GI) homeostasis (1). Recent advances in microbiome research have revealed its profound influence on various GI diseases, such as gastric cancer, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), acute pancreatitis, and Clostridioides difficile infection (CDI) (2). Understanding the interplay between the gut microbiota and these conditions offers promising avenues for novel therapeutic interventions, including next-generation probiotics, fecal microbiota transplantation (FMT), and targeted microbiome-directed modulation (3, 4).