TY - JOUR
T1 - Effects of construct stiffness on healing of fractures stabilized with locking plates
AU - Bottlang, Michael
AU - Doornink, Josef
AU - Lujan, Trevor J.
AU - Fitzpatrick, Daniel C.
AU - Marsh, J. Lawrence
AU - Augat, Peter
AU - Von Rechenberg, Brigitte
AU - Lesser, Maren
AU - Madey, Steven M.
PY - 2010/12/1
Y1 - 2010/12/1
N2 - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.
AB - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.
UR - http://www.scopus.com/inward/record.url?scp=78649882661&partnerID=8YFLogxK
UR - https://doi.org/10.2106/JBJS.J.00780
U2 - 10.2106/JBJS.J.00780
DO - 10.2106/JBJS.J.00780
M3 - Article
C2 - 21123589
AN - SCOPUS:78649882661
SN - 0021-9355
VL - 92
SP - 12
EP - 22
JO - Journal of Bone and Joint Surgery
JF - Journal of Bone and Joint Surgery
IS - SUPPL. 2
ER -