Effects of construct stiffness on healing of fractures stabilized with locking plates

Michael Bottlang, Josef Doornink, Trevor J. Lujan, Daniel C. Fitzpatrick, J. Lawrence Marsh, Peter Augat, Brigitte Von Rechenberg, Maren Lesser, Steven M. Madey

Research output: Contribution to journalArticlepeer-review

152 Scopus citations

Abstract

The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.
Original languageEnglish
Pages (from-to)12-22
Number of pages11
JournalJournal of Bone and Joint Surgery
Volume92
Issue numberSUPPL. 2
DOIs
StatePublished - 1 Dec 2010

EGS Disciplines

  • Biomedical Engineering and Bioengineering
  • Materials Science and Engineering

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