Effects of construct stiffness on healing of fractures stabilized with locking plates

Michael Bottlang; Josef Doornink; Trevor J. Lujan; Daniel C. Fitzpatrick; J. Lawrence Marsh; Peter Augat; Brigitte Von Rechenberg; Maren Lesser; Steven M. Madey

doi:10.2106/JBJS.J.00780

Effects of construct stiffness on healing of fractures stabilized with locking plates

Michael Bottlang
, Josef Doornink
, Trevor J. Lujan
, Daniel C. Fitzpatrick
, J. Lawrence Marsh
, Peter Augat
, Brigitte Von Rechenberg
, Maren Lesser
, Steven M. Madey

Mechanical and Biomedical Engineering Department

Legacy Biomechanics Laboratory
University of Iowa
Institute of Biomechanics
University of Zurich
University of Iowa Hospitals and Clinics

Research output: Contribution to journal › Article › peer-review

172 Scopus citations

Abstract

The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

Original language	English
Pages (from-to)	12-22
Number of pages	11
Journal	Journal of Bone and Joint Surgery
Volume	92
Issue number	SUPPL. 2
DOIs	https://doi.org/10.2106/JBJS.J.00780
State	Published - 1 Dec 2010

Keywords

Bone Plates
Fracture Healing/physiology
Fractures, Bone/surgery
Humans
Orthopedic Procedures/instrumentation
Treatment Outcome

EGS Disciplines

Biomedical Engineering and Bioengineering
Materials Science and Engineering

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10.2106/JBJS.J.00780

Cite this

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title = "Effects of construct stiffness on healing of fractures stabilized with locking plates",

abstract = " The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion. ",

keywords = "Bone Plates, Fracture Healing/physiology, Fractures, Bone/surgery, Humans, Orthopedic Procedures/instrumentation, Treatment Outcome",

author = "Michael Bottlang and Josef Doornink and Lujan, \{Trevor J.\} and Fitzpatrick, \{Daniel C.\} and Marsh, \{J. Lawrence\} and Peter Augat and \{Von Rechenberg\}, Brigitte and Maren Lesser and Madey, \{Steven M.\}",

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doi = "10.2106/JBJS.J.00780",

language = "English",

volume = "92",

pages = "12--22",

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TY - JOUR

T1 - Effects of construct stiffness on healing of fractures stabilized with locking plates

AU - Bottlang, Michael

AU - Doornink, Josef

AU - Lujan, Trevor J.

AU - Fitzpatrick, Daniel C.

AU - Marsh, J. Lawrence

AU - Augat, Peter

AU - Von Rechenberg, Brigitte

AU - Lesser, Maren

AU - Madey, Steven M.

PY - 2010/12/1

Y1 - 2010/12/1

N2 - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

AB - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

KW - Bone Plates

KW - Fracture Healing/physiology

KW - Fractures, Bone/surgery

KW - Humans

KW - Orthopedic Procedures/instrumentation

KW - Treatment Outcome

UR - https://www.scopus.com/pages/publications/78649882661

U2 - 10.2106/JBJS.J.00780

DO - 10.2106/JBJS.J.00780

M3 - Article

C2 - 21123589

AN - SCOPUS:78649882661

SN - 0021-9355

VL - 92

SP - 12

EP - 22

JO - Journal of Bone and Joint Surgery

JF - Journal of Bone and Joint Surgery

IS - SUPPL. 2

ER -

Effects of construct stiffness on healing of fractures stabilized with locking plates

Abstract

Keywords

EGS Disciplines

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