Effects of construct stiffness on healing of fractures stabilized with locking plates

Michael Bottlang; Josef Doornink; Trevor J. Lujan; Daniel C. Fitzpatrick; J. Lawrence Marsh; Peter Augat; Brigitte Von Rechenberg; Maren Lesser; Steven M. Madey

doi:10.2106/JBJS.J.00780

Effects of construct stiffness on healing of fractures stabilized with locking plates

Michael Bottlang, Josef Doornink, Trevor J. Lujan, Daniel C. Fitzpatrick, J. Lawrence Marsh, Peter Augat, Brigitte Von Rechenberg, Maren Lesser, Steven M. Madey

Mechanical and Biomedical Engineering Department

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Abstract

The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

Original language	English
Pages (from-to)	12-22
Number of pages	11
Journal	Journal of Bone and Joint Surgery
Volume	92
Issue number	SUPPL. 2
DOIs	https://doi.org/10.2106/JBJS.J.00780
State	Published - 1 Dec 2010

Keywords

Bone Plates
Fracture Healing/physiology
Fractures, Bone/surgery
Humans
Orthopedic Procedures/instrumentation
Treatment Outcome

EGS Disciplines

Biomedical Engineering and Bioengineering
Materials Science and Engineering

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10.2106/JBJS.J.00780

Cite this

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title = "Effects of construct stiffness on healing of fractures stabilized with locking plates",

abstract = " The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion. ",

keywords = "Bone Plates, Fracture Healing/physiology, Fractures, Bone/surgery, Humans, Orthopedic Procedures/instrumentation, Treatment Outcome",

author = "Michael Bottlang and Josef Doornink and Lujan, \{Trevor J.\} and Fitzpatrick, \{Daniel C.\} and Marsh, \{J. Lawrence\} and Peter Augat and \{Von Rechenberg\}, Brigitte and Maren Lesser and Madey, \{Steven M.\}",

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doi = "10.2106/JBJS.J.00780",

language = "English",

volume = "92",

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TY - JOUR

T1 - Effects of construct stiffness on healing of fractures stabilized with locking plates

AU - Bottlang, Michael

AU - Doornink, Josef

AU - Lujan, Trevor J.

AU - Fitzpatrick, Daniel C.

AU - Marsh, J. Lawrence

AU - Augat, Peter

AU - Von Rechenberg, Brigitte

AU - Lesser, Maren

AU - Madey, Steven M.

PY - 2010/12/1

Y1 - 2010/12/1

N2 - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

AB - The benefits of locked-plate fixation, which include improved fixation strength in osteoporotic bone and the ability to provide a more biologically friendly fixation construct, have led to the rapid adoption of this technology. Biological fixation of comminuted fractures with locking plates relies on secondary fracture-healing by callus formation, which is stimulated by interfragmentary motion in the millimeter range. Secondary bone-healing can be enhanced by active or passive dynamization. Conversely, bone-healing can be suppressed by rigid fracture fixation aimed at preventing interfragmentary motion.

KW - Bone Plates

KW - Fracture Healing/physiology

KW - Fractures, Bone/surgery

KW - Humans

KW - Orthopedic Procedures/instrumentation

KW - Treatment Outcome

UR - https://www.scopus.com/pages/publications/78649882661

UR - https://doi.org/10.2106/JBJS.J.00780

U2 - 10.2106/JBJS.J.00780

DO - 10.2106/JBJS.J.00780

M3 - Article

C2 - 21123589

AN - SCOPUS:78649882661

SN - 0021-9355

VL - 92

SP - 12

EP - 22

JO - Journal of Bone and Joint Surgery

JF - Journal of Bone and Joint Surgery

IS - SUPPL. 2

ER -

Effects of construct stiffness on healing of fractures stabilized with locking plates

Abstract

Keywords

EGS Disciplines

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