TY - JOUR
T1 - Experimental Versus Numerical Data for Breast Cancer Progression
AU - Jorcyk, Cheryl L.
AU - Kolev, M.
AU - Tawara, Ken
AU - Zubik-Kowal, Barbara
PY - 2012/2/1
Y1 - 2012/2/1
N2 - This paper deals with a mouse model of breast cancer based on two mammary adenocarcinoma cell lines derived from a spontaneous tumor of the mammary gland in a female BALB/c mouse. We investigate both animal and mathematical models of tumor progression, and demonstrate a correspondence between the experimental and predicted data. The mathematical model is solved numerically and the laboratory data are utilized in order to find unknown parameters for the model equations. The results of the numerical experiments illustrate that the mathematical model has a potential to describe the growth of cancer cells in vivo.
AB - This paper deals with a mouse model of breast cancer based on two mammary adenocarcinoma cell lines derived from a spontaneous tumor of the mammary gland in a female BALB/c mouse. We investigate both animal and mathematical models of tumor progression, and demonstrate a correspondence between the experimental and predicted data. The mathematical model is solved numerically and the laboratory data are utilized in order to find unknown parameters for the model equations. The results of the numerical experiments illustrate that the mathematical model has a potential to describe the growth of cancer cells in vivo.
KW - cell lines
KW - mammary
KW - tumor progression
KW - animal model
KW - integro-differential equations
UR - https://scholarworks.boisestate.edu/bio_facpubs/158
UR - http://dx.doi.org/10.1016/j.nonrwa.2011.07.014
U2 - 10.1016/j.nonrwa.2011.07.014
DO - 10.1016/j.nonrwa.2011.07.014
M3 - Article
SN - 1468-1218
JO - Nonlinear Analysis: Real World Applications
JF - Nonlinear Analysis: Real World Applications
ER -
