Extracellular matrix in development and disease

Julia Thom Oxford; Jonathon C. Reeck; Makenna J. Hardy

doi:10.3390/ijms20010205

Extracellular matrix in development and disease

Julia Thom Oxford, Jonathon C. Reeck, Makenna J. Hardy

Department of Biological Sciences

Boise State University

Research output: Contribution to journal › Editorial

27 Scopus citations

Abstract

The evolution of multicellular metazoan organisms was marked by the inclusion of an extracellular matrix (ECM), a multicomponent, proteinaceous network between cells that contributes to the spatial arrangement of cells and the resulting tissue organization. The development of an ECM that provides support in larger organisms may have represented an advantage in the face of selection pressure for the evolution of the ECM.

Original language	English
Article number	205
Journal	International Journal of Molecular Sciences
Volume	20
Issue number	1
DOIs	https://doi.org/10.3390/ijms20010205
State	Published - 1 Jan 2019

Keywords

Cancer
Extracellular matrix
Hereditary diseases
Integrins
Muscle
Reproduction
Tissue engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/ijms20010205

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title = "Extracellular matrix in development and disease",

abstract = " The evolution of multicellular metazoan organisms was marked by the inclusion of an extracellular matrix (ECM), a multicomponent, proteinaceous network between cells that contributes to the spatial arrangement of cells and the resulting tissue organization. The development of an ECM that provides support in larger organisms may have represented an advantage in the face of selection pressure for the evolution of the ECM.",

keywords = "Cancer, Extracellular matrix, Hereditary diseases, Integrins, Muscle, Reproduction, Tissue engineering",

author = "Oxford, {Julia Thom} and Reeck, {Jonathon C.} and Hardy, {Makenna J.}",

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AU - Oxford, Julia Thom

AU - Reeck, Jonathon C.

AU - Hardy, Makenna J.

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N2 - The evolution of multicellular metazoan organisms was marked by the inclusion of an extracellular matrix (ECM), a multicomponent, proteinaceous network between cells that contributes to the spatial arrangement of cells and the resulting tissue organization. The development of an ECM that provides support in larger organisms may have represented an advantage in the face of selection pressure for the evolution of the ECM.

AB - The evolution of multicellular metazoan organisms was marked by the inclusion of an extracellular matrix (ECM), a multicomponent, proteinaceous network between cells that contributes to the spatial arrangement of cells and the resulting tissue organization. The development of an ECM that provides support in larger organisms may have represented an advantage in the face of selection pressure for the evolution of the ECM.

KW - Cancer

KW - Extracellular matrix

KW - Hereditary diseases

KW - Integrins

KW - Muscle

KW - Reproduction

KW - Tissue engineering

UR - http://www.scopus.com/inward/record.url?scp=85059795430&partnerID=8YFLogxK

U2 - 10.3390/ijms20010205

DO - 10.3390/ijms20010205

M3 - Editorial

C2 - 30626024

SN - 1661-6596

VL - 20

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

IS - 1

M1 - 205

ER -

Extracellular matrix in development and disease

Abstract

Keywords

UN SDGs

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