TY - JOUR
T1 - Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank
AU - Alfaro-Almagro, Fidel
AU - Jenkinson, Mark
AU - Bangerter, Neal K.
AU - Andersson, Jesper L.R.
AU - Griffanti, Ludovica
AU - Douaud, Gwenaëlle
AU - Sotiropoulos, Stamatios N.
AU - Jbabdi, Saad
AU - Hernandez-Fernandez, Moises
AU - Vallee, Emmanuel
AU - Vidaurre, Diego
AU - Webster, Matthew
AU - McCarthy, Paul
AU - Rorden, Christopher
AU - Daducci, Alessandro
AU - Alexander, Daniel C.
AU - Zhang, Hui
AU - Dragonu, Iulius
AU - Matthews, Paul M.
AU - Miller, Karla L.
AU - Smith, Stephen M.
N1 - Publisher Copyright:
© 2017 The Authors
PY - 2018/2/1
Y1 - 2018/2/1
N2 - UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.
AB - UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.
KW - Big data imaging
KW - Epidemiological studies
KW - Image analysis pipeline
KW - Machine learning
KW - Multi-modal data integration
KW - Quality control
UR - http://www.scopus.com/inward/record.url?scp=85034842645&partnerID=8YFLogxK
U2 - 10.1016/j.neuroimage.2017.10.034
DO - 10.1016/j.neuroimage.2017.10.034
M3 - Article
C2 - 29079522
AN - SCOPUS:85034842645
SN - 1053-8119
VL - 166
SP - 400
EP - 424
JO - NeuroImage
JF - NeuroImage
ER -