Label-free imaging of metal-carbonyl complexes in live cells by raman microspectroscopy

Konrad Meister; Johanna Niesel; Ulrich Schatzschneider; Nils Metzler-Nolte; Diedrich A. Schmidt; Martina Havenith

doi:10.1002/anie.201000097

Label-free imaging of metal-carbonyl complexes in live cells by raman microspectroscopy

Konrad Meister
, Johanna Niesel
, Ulrich Schatzschneider
, Nils Metzler-Nolte
, Diedrich A. Schmidt
, Martina Havenith

Chemistry Department

Ruhr University Bochum

Research output: Contribution to journal › Article › peer-review

165 Scopus citations

Abstract

(Figure Presented) A new kid in town: 3D Raman intensity images of a HT29 colon cancer cell incubated with an aqueous solution of the CO-releasing metal-carbonyl complex 1 show that the compound penetrates the cellular membrane and is localized mainly in the nuclear membrane and the nuclelus. The C≡O vibration of l serves as an intrinsic spectroscopic label.

Original language	English
Pages (from-to)	3310-3312
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	19
DOIs	https://doi.org/10.1002/anie.201000097
State	Published - 26 Apr 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bioorganometallic chemistry
Infrared microscopy
Medicinal chemistry
Metal-carbonyl complexes
Molecular imaging

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10.1002/anie.201000097

Cite this

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title = "Label-free imaging of metal-carbonyl complexes in live cells by raman microspectroscopy",

abstract = "(Figure Presented) A new kid in town: 3D Raman intensity images of a HT29 colon cancer cell incubated with an aqueous solution of the CO-releasing metal-carbonyl complex 1 show that the compound penetrates the cellular membrane and is localized mainly in the nuclear membrane and the nuclelus. The C≡O vibration of l serves as an intrinsic spectroscopic label.",

keywords = "Bioorganometallic chemistry, Infrared microscopy, Medicinal chemistry, Metal-carbonyl complexes, Molecular imaging",

author = "Konrad Meister and Johanna Niesel and Ulrich Schatzschneider and Nils Metzler-Nolte and Schmidt, \{Diedrich A.\} and Martina Havenith",

year = "2010",

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doi = "10.1002/anie.201000097",

language = "English",

volume = "49",

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T1 - Label-free imaging of metal-carbonyl complexes in live cells by raman microspectroscopy

AU - Meister, Konrad

AU - Niesel, Johanna

AU - Schatzschneider, Ulrich

AU - Metzler-Nolte, Nils

AU - Schmidt, Diedrich A.

AU - Havenith, Martina

PY - 2010/4/26

Y1 - 2010/4/26

N2 - (Figure Presented) A new kid in town: 3D Raman intensity images of a HT29 colon cancer cell incubated with an aqueous solution of the CO-releasing metal-carbonyl complex 1 show that the compound penetrates the cellular membrane and is localized mainly in the nuclear membrane and the nuclelus. The C≡O vibration of l serves as an intrinsic spectroscopic label.

AB - (Figure Presented) A new kid in town: 3D Raman intensity images of a HT29 colon cancer cell incubated with an aqueous solution of the CO-releasing metal-carbonyl complex 1 show that the compound penetrates the cellular membrane and is localized mainly in the nuclear membrane and the nuclelus. The C≡O vibration of l serves as an intrinsic spectroscopic label.

KW - Bioorganometallic chemistry

KW - Infrared microscopy

KW - Medicinal chemistry

KW - Metal-carbonyl complexes

KW - Molecular imaging

UR - https://www.scopus.com/pages/publications/77951669928

U2 - 10.1002/anie.201000097

DO - 10.1002/anie.201000097

M3 - Article

C2 - 20349485

AN - SCOPUS:77951669928

SN - 1433-7851

VL - 49

SP - 3310

EP - 3312

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 19

ER -

Label-free imaging of metal-carbonyl complexes in live cells by raman microspectroscopy

Abstract

UN SDGs

Keywords

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