MEDUSA: A Low-Cost, 16-Channel Neuromodulation Platform with Arbitrary Waveform Generation: A low-cost, 16-channel neuromodulation platform with arbitrary waveform generation

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3 Scopus citations

Abstract

Neural stimulation systems are used to modulate electrically excitable tissue to interrogate neural circuit function or provide therapeutic benefit. Conventional stimulation systems are expensive and limited in functionality to standard stimulation waveforms, and they are bad for high frequency stimulation. We present MEDUSA, a system that enables new research applications that can leverage multi-channel, arbitrary stimulation waveforms. MEDUSA is low cost and uses commercially available components for widespread adoption. MEDUSA is comprised of a PC interface, an FPGA for precise timing control, and eight bipolar current sources that can each address up to 16 electrodes. The current sources have a resolution of 15.3 nA and can provide ±5 mA with ±5 V compliance. We demonstrate charge-balancing techniques in vitro using a custom microelectrode. An in vivo strength-duration curve for earthworm nerve activation is also constructed using MEDUSA. MEDUSA is a multi-functional neuroscience research tool for electroplating microelectrodes, performing electrical impedance spectroscopy, and examining novel neural stimulation protocols.

Original languageAmerican English
Article number812
JournalElectrical and Computer Engineering Faculty Publications and Presentations
Volume9
Issue number5
DOIs
StatePublished - 1 May 2020

Keywords

  • FPGA
  • multi-channel
  • neuromodulation
  • stimulation protocol

EGS Disciplines

  • Electrical and Computer Engineering

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