Microbiota Manipulation as a Metagenomic Therapeutic Approach for Rare Inherited Metabolic Disorders

Trevor O. Kirby; Madalyn Brown; Javier Ochoa-Reparaz; Jean-Baptiste Roullet; K. Michael Gibson

doi:10.1002/cpt.1503

Microbiota Manipulation as a Metagenomic Therapeutic Approach for Rare Inherited Metabolic Disorders

Trevor O. Kirby, Madalyn Brown, Javier Ochoa-Reparaz, Jean-Baptiste Roullet, K. Michael Gibson

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Original language	American English
Pages (from-to)	505-507
Number of pages	3
Journal	Clinical Pharmacology & Therapeutics
Volume	106
Issue number	3
Early online date	13 Aug 2019
DOIs	https://doi.org/10.1002/cpt.1503
State	Published - Sep 2019
Externally published	Yes

Keywords

Severity of Illness Index
Rare Diseases/physiopathology
Humans
Probiotics/administration & dosage
Prebiotics/administration & dosage
Amino Acid Metabolism, Inborn Errors/physiopathology
Animals
Succinate-Semialdehyde Dehydrogenase/deficiency
Gastrointestinal Microbiome/physiology
RNA, Ribosomal, 16S/metabolism
4-Aminobutyrate Transaminase/deficiency
Metabolism, Inborn Errors/physiopathology
Mice
Developmental Disabilities/physiopathology
Fecal Microbiota Transplantation/methods

EGS Disciplines

Biology

Access to Document

10.1002/cpt.1503License: Unspecified

Cite this

@article{9a4b0315c47148a698fa2e47e9414e96,

title = "Microbiota Manipulation as a Metagenomic Therapeutic Approach for Rare Inherited Metabolic Disorders",

keywords = "Severity of Illness Index, Rare Diseases/physiopathology, Humans, Probiotics/administration \& dosage, Prebiotics/administration \& dosage, Amino Acid Metabolism, Inborn Errors/physiopathology, Animals, Succinate-Semialdehyde Dehydrogenase/deficiency, Gastrointestinal Microbiome/physiology, RNA, Ribosomal, 16S/metabolism, 4-Aminobutyrate Transaminase/deficiency, Metabolism, Inborn Errors/physiopathology, Mice, Developmental Disabilities/physiopathology, Fecal Microbiota Transplantation/methods",

author = "Kirby, \{Trevor O.\} and Madalyn Brown and Javier Ochoa-Reparaz and Jean-Baptiste Roullet and Gibson, \{K. Michael\}",

year = "2019",

month = sep,

doi = "10.1002/cpt.1503",

language = "American English",

volume = "106",

pages = "505--507",

number = "3",

}

TY - JOUR

T1 - Microbiota Manipulation as a Metagenomic Therapeutic Approach for Rare Inherited Metabolic Disorders

AU - Kirby, Trevor O.

AU - Brown, Madalyn

AU - Ochoa-Reparaz, Javier

AU - Roullet, Jean-Baptiste

AU - Gibson, K. Michael

PY - 2019/9

Y1 - 2019/9

KW - Severity of Illness Index

KW - Rare Diseases/physiopathology

KW - Humans

KW - Probiotics/administration & dosage

KW - Prebiotics/administration & dosage

KW - Amino Acid Metabolism, Inborn Errors/physiopathology

KW - Animals

KW - Succinate-Semialdehyde Dehydrogenase/deficiency

KW - Gastrointestinal Microbiome/physiology

KW - RNA, Ribosomal, 16S/metabolism

KW - 4-Aminobutyrate Transaminase/deficiency

KW - Metabolism, Inborn Errors/physiopathology

KW - Mice

KW - Developmental Disabilities/physiopathology

KW - Fecal Microbiota Transplantation/methods

U2 - 10.1002/cpt.1503

DO - 10.1002/cpt.1503

M3 - Article

C2 - 31273774

VL - 106

SP - 505

EP - 507

JO - Clinical Pharmacology & Therapeutics

JF - Clinical Pharmacology & Therapeutics

IS - 3

ER -

Microbiota Manipulation as a Metagenomic Therapeutic Approach for Rare Inherited Metabolic Disorders

Keywords

EGS Disciplines

Access to Document

Fingerprint

Cite this