Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes

Eric C. Brown; Brandon Johnson; Sara Palavicini; Benjamin E. Kucera; Luigi Casella; William B. Tolman

doi:10.1039/b705806c

Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes

Eric C. Brown, Brandon Johnson, Sara Palavicini, Benjamin E. Kucera, Luigi Casella, William B. Tolman

Chemistry Department

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites.

Original language	English
Pages (from-to)	3035-3042
Number of pages	8
Journal	Dalton Transactions
Issue number	28
DOIs	https://doi.org/10.1039/b705806c
State	Published - 28 Jul 2007

Keywords

Copper/chemistry
Crystallography, X-Ray
Electric Conductivity
Ligands
Models, Molecular
Molecular Structure
Nitrogen/chemistry

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10.1039/b705806c

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title = "Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes",

abstract = "A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites.",

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author = "Brown, \{Eric C.\} and Brandon Johnson and Sara Palavicini and Kucera, \{Benjamin E.\} and Luigi Casella and Tolman, \{William B.\}",

year = "2007",

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doi = "10.1039/b705806c",

language = "English",

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T1 - Modular syntheses of multidentate ligands with variable N-donors

T2 - Applications to tri- and tetracopper(i) complexes

AU - Brown, Eric C.

AU - Johnson, Brandon

AU - Palavicini, Sara

AU - Kucera, Benjamin E.

AU - Casella, Luigi

AU - Tolman, William B.

PY - 2007/7/28

Y1 - 2007/7/28

N2 - A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites.

AB - A general method for the preparation of multidentate ligands comprised of a multi-imine platform derived from 1,1,1-tris(aminomethyl)ethane or tris(aminoethyl)amine connected to bi- and tridentate N-donor chelates has been developed. The feasibility of the method has been demonstrated through the synthesis and characterization of a large set of these ligand types. Complexation to Cu(i) was accomplished for several cases, yielding tri- and tetracopper(i) complexes that have been characterized in solution by NMR spectroscopy and conductivity, and in the solid state by elemental analysis, mass spectrometry, and/or X-ray crystallography. These complexes are potentially useful for modeling multicopper protein active sites.

KW - Copper/chemistry

KW - Crystallography, X-Ray

KW - Electric Conductivity

KW - Ligands

KW - Models, Molecular

KW - Molecular Structure

KW - Nitrogen/chemistry

UR - https://www.scopus.com/pages/publications/34547490009

U2 - 10.1039/b705806c

DO - 10.1039/b705806c

M3 - Article

C2 - 17622421

AN - SCOPUS:34547490009

SN - 1477-9226

SP - 3035

EP - 3042

JO - Dalton Transactions

JF - Dalton Transactions

IS - 28

ER -

Modular syntheses of multidentate ligands with variable N-donors: Applications to tri- and tetracopper(i) complexes

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Keywords

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