Operation Kinetics of a DNA-Based Molecular Switch

Friedrich C. Simmel; Bernard Yurke; Rishi J. Sanyal

doi:10.1166/jnn.2002.122

Operation Kinetics of a DNA-Based Molecular Switch

Friedrich C. Simmel
, Bernard Yurke
, Rishi J. Sanyal

Nokia
Ludwig Maximilian University of Munich
Princeton University

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The influence of temperature variation, salt concentration, and pH on the operation kinetics of a simple DNA-based molecular switch is investigated. The device shows robust behavior over a wide range of temperatures, pH, and salt concentrations. In particular, the device operates well under physiological conditions. The experimental data can be qualitatively understood in terms of the influence temperature, salt concentration, and pH have on DNA strand interactions.

Original language	English
Pages (from-to)	383-390
Number of pages	8
Journal	Journal of Nanoscience and Nanotechnology
Volume	2
Issue number	3-4
DOIs	https://doi.org/10.1166/jnn.2002.122
State	Published - Jun 2002
Externally published	Yes

Keywords

DNA
Molecular Machines
Self-Assembly

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10.1166/jnn.2002.122

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title = "Operation Kinetics of a DNA-Based Molecular Switch",

abstract = "The influence of temperature variation, salt concentration, and pH on the operation kinetics of a simple DNA-based molecular switch is investigated. The device shows robust behavior over a wide range of temperatures, pH, and salt concentrations. In particular, the device operates well under physiological conditions. The experimental data can be qualitatively understood in terms of the influence temperature, salt concentration, and pH have on DNA strand interactions.",

keywords = "DNA, Molecular Machines, Self-Assembly",

author = "Simmel, \{Friedrich C.\} and Bernard Yurke and Sanyal, \{Rishi J.\}",

year = "2002",

month = jun,

doi = "10.1166/jnn.2002.122",

language = "English",

volume = "2",

pages = "383--390",

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T1 - Operation Kinetics of a DNA-Based Molecular Switch

AU - Simmel, Friedrich C.

AU - Yurke, Bernard

AU - Sanyal, Rishi J.

PY - 2002/6

Y1 - 2002/6

N2 - The influence of temperature variation, salt concentration, and pH on the operation kinetics of a simple DNA-based molecular switch is investigated. The device shows robust behavior over a wide range of temperatures, pH, and salt concentrations. In particular, the device operates well under physiological conditions. The experimental data can be qualitatively understood in terms of the influence temperature, salt concentration, and pH have on DNA strand interactions.

AB - The influence of temperature variation, salt concentration, and pH on the operation kinetics of a simple DNA-based molecular switch is investigated. The device shows robust behavior over a wide range of temperatures, pH, and salt concentrations. In particular, the device operates well under physiological conditions. The experimental data can be qualitatively understood in terms of the influence temperature, salt concentration, and pH have on DNA strand interactions.

KW - DNA

KW - Molecular Machines

KW - Self-Assembly

UR - https://www.scopus.com/pages/publications/0347625199

U2 - 10.1166/jnn.2002.122

DO - 10.1166/jnn.2002.122

M3 - Article

C2 - 12908267

AN - SCOPUS:0347625199

SN - 1533-4880

VL - 2

SP - 383

EP - 390

JO - Journal of Nanoscience and Nanotechnology

JF - Journal of Nanoscience and Nanotechnology

IS - 3-4

ER -

Operation Kinetics of a DNA-Based Molecular Switch

Abstract

Keywords

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