Organization of lipids in fiber-cell plasma membranes of the eye lens

Witold K. Subczynski; Laxman Mainali; Marija Raguz; William J. O'Brien

doi:10.1016/j.exer.2016.03.004

Organization of lipids in fiber-cell plasma membranes of the eye lens

Witold K. Subczynski
, Laxman Mainali
, Marija Raguz
, William J. O'Brien

Physics Department

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

The plasma membrane together with the cytoskeleton forms the only supramolecular structure of the matured fiber cell which accounts for mostly all fiber cell lipids. The purpose of this review is to inform researchers about the importance of the lipid bilayer portion of the lens fiber cell plasma membranes in the maintaining lens homeostasis, and thus protecting against cataract development.

Original language	English
Pages (from-to)	79-86
Number of pages	8
Journal	Experimental Eye Research
Volume	156
Early online date	14 Mar 2016
DOIs	https://doi.org/10.1016/j.exer.2016.03.004
State	Published - Mar 2017

Keywords

Cholesterol
Cholesterol bilayer domain
Cholesterol crystals
Membrane domains
Oxygen permeation
Spin labeling

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10.1016/j.exer.2016.03.004

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title = "Organization of lipids in fiber-cell plasma membranes of the eye lens",

abstract = "The plasma membrane together with the cytoskeleton forms the only supramolecular structure of the matured fiber cell which accounts for mostly all fiber cell lipids. The purpose of this review is to inform researchers about the importance of the lipid bilayer portion of the lens fiber cell plasma membranes in the maintaining lens homeostasis, and thus protecting against cataract development.",

keywords = "Cholesterol, Cholesterol bilayer domain, Cholesterol crystals, Membrane domains, Oxygen permeation, Spin labeling",

author = "Subczynski, \{Witold K.\} and Laxman Mainali and Marija Raguz and O'Brien, \{William J.\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Ltd",

year = "2017",

month = mar,

doi = "10.1016/j.exer.2016.03.004",

language = "English",

volume = "156",

pages = "79--86",

journal = "Experimental Eye Research",

issn = "0014-4835",

publisher = "Academic Press",

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T1 - Organization of lipids in fiber-cell plasma membranes of the eye lens

AU - Subczynski, Witold K.

AU - Mainali, Laxman

AU - Raguz, Marija

AU - O'Brien, William J.

PY - 2017/3

Y1 - 2017/3

N2 - The plasma membrane together with the cytoskeleton forms the only supramolecular structure of the matured fiber cell which accounts for mostly all fiber cell lipids. The purpose of this review is to inform researchers about the importance of the lipid bilayer portion of the lens fiber cell plasma membranes in the maintaining lens homeostasis, and thus protecting against cataract development.

AB - The plasma membrane together with the cytoskeleton forms the only supramolecular structure of the matured fiber cell which accounts for mostly all fiber cell lipids. The purpose of this review is to inform researchers about the importance of the lipid bilayer portion of the lens fiber cell plasma membranes in the maintaining lens homeostasis, and thus protecting against cataract development.

KW - Cholesterol

KW - Cholesterol bilayer domain

KW - Cholesterol crystals

KW - Membrane domains

KW - Oxygen permeation

KW - Spin labeling

UR - https://www.scopus.com/pages/publications/84961221152

U2 - 10.1016/j.exer.2016.03.004

DO - 10.1016/j.exer.2016.03.004

M3 - Article

C2 - 26988627

AN - SCOPUS:84961221152

SN - 0014-4835

VL - 156

SP - 79

EP - 86

JO - Experimental Eye Research

JF - Experimental Eye Research

ER -

Organization of lipids in fiber-cell plasma membranes of the eye lens

Abstract

Keywords

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