Parkinson’s disease and enhanced inflammatory response

Iva Stojkovska, Brandon M. Wagner, Brad E. Morrison

Research output: Contribution to journalReview articlepeer-review

124 Scopus citations

Abstract

Parkinson’s disease (PD) is the first and second most prevalent motor and neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of midbrain dopaminergic (DA) neurons. However, the molecular cause of DA neuron loss remains elusive. Mounting evidence implicates enhanced inflammatory response in the development and progression of PD pathology. This review examines current research connecting PD and inflammatory response.

Original languageEnglish
Pages (from-to)1387-1395
Number of pages9
JournalExperimental Biology and Medicine
Volume240
Issue number11
DOIs
StatePublished - 1 Nov 2015

Keywords

  • disease models
  • inflammation
  • neuroinflammation
  • Parkinson’s disease

Fingerprint

Dive into the research topics of 'Parkinson’s disease and enhanced inflammatory response'. Together they form a unique fingerprint.

Cite this