Abstract
Parkinson’s disease (PD) is the first and second most prevalent motor and neurodegenerative disease, respectively. The clinical symptoms of PD result from a loss of midbrain dopaminergic (DA) neurons. However, the molecular cause of DA neuron loss remains elusive. Mounting evidence implicates enhanced inflammatory response in the development and progression of PD pathology. This review examines current research connecting PD and inflammatory response.
Original language | English |
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Pages (from-to) | 1387-1395 |
Number of pages | 9 |
Journal | Experimental Biology and Medicine |
Volume | 240 |
Issue number | 11 |
DOIs | |
State | Published - 1 Nov 2015 |
Keywords
- disease models
- inflammation
- neuroinflammation
- Parkinson’s disease