TY - GEN
T1 - Prototype continuous flow polymerase chain reaction LTCC device
T2 - 2nd International Conference and Exhibition on Ceramic Interconnect and Ceramic Microsystems Technologies, CICMT 2006
AU - Moeller, K.
AU - Besecker, J.
AU - Hampikian, G.
AU - Hampikian, J. M.
AU - Moll, A.
AU - Plumlee, D.
AU - Youngsman, J.
PY - 2006
Y1 - 2006
N2 - Remote biological sensing in both laboratory and harsh field environments is a growing need. Sensing and detection of biological entities such as anthrax, Ebola and other micro-organisms of interest involves sampling of the environment, amplification, analysis and identification of the target DNA. A key component of such a sensor is a miniaturized thermal cycler for polymerase chain reaction (PCR). Fabrication with low temperature co-fired ceramics (LTCC) can provide a reusable low cost device capable of operating in a wide range of environments The design, manufacture and biocompatibility of a prototype continuous flow micro-fluidic PCR device using low temperature co-fired ceramic is presented. The prototype device employs resistance heaters below the channels, buried and surface thermocouples for temperature monitoring, and air gaps for thermal isolation.
AB - Remote biological sensing in both laboratory and harsh field environments is a growing need. Sensing and detection of biological entities such as anthrax, Ebola and other micro-organisms of interest involves sampling of the environment, amplification, analysis and identification of the target DNA. A key component of such a sensor is a miniaturized thermal cycler for polymerase chain reaction (PCR). Fabrication with low temperature co-fired ceramics (LTCC) can provide a reusable low cost device capable of operating in a wide range of environments The design, manufacture and biocompatibility of a prototype continuous flow micro-fluidic PCR device using low temperature co-fired ceramic is presented. The prototype device employs resistance heaters below the channels, buried and surface thermocouples for temperature monitoring, and air gaps for thermal isolation.
UR - https://www.scopus.com/pages/publications/84878218399
M3 - Conference contribution
AN - SCOPUS:84878218399
SN - 9781604236200
T3 - IMAPS/ACerS - 2nd International Conference and Exhibition on Ceramic Interconnect and Ceramic Microsystems Technologies, CICMT 2006
SP - 358
EP - 361
BT - IMAPS/ACerS - 2nd International Conference and Exhibition on Ceramic Interconnect and Ceramic Microsystems Technologies, CICMT 2006
Y2 - 24 April 2006 through 27 April 2006
ER -
