StimDust: A 6.5mm3, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency

Benjamin C. Johnson; Konlin Shen; David Piech; M. Meraj Ghanbari; Ka Yiu Li; Ryan Neely; Jose M. Carmena; Michel M. Maharbiz; Rikky Muller

doi:10.1109/CICC.2018.8357047

StimDust: A 6.5mm³, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency

Benjamin C. Johnson, Konlin Shen, David Piech, M. Meraj Ghanbari, Ka Yiu Li, Ryan Neely, Jose M. Carmena, Michel M. Maharbiz, Rikky Muller

Electrical Engineering Department

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

62 Scopus citations

Abstract

We present a 6.5mm³, 10mg, wireless peripheral nerve stimulator. The stimulator is powered and controlled through ultrasound from an external transducer and utilizes a single 750×750×750μm³ piezocrystal for downlink communication, powering, and readout, reducing implant volume and mass. An IC with 0.06mm² active circuit area, designed in TSMC 65nm LPCMOS process, converts harvested ultrasound to stimulation charge with a peak efficiency of 82%. A custom wireless protocol that does not require a clock or memory circuits reduces on-chip power to 4μW when not stimulating. The encapsulated stimulator was cuffed to the sciatic nerve of an anesthetized rodent and demonstrated full-scale nerve activation in vivo. We achieve a highly efficient and temporally precise wireless peripheral nerve stimulator that is the smallest and lightest to our knowledge.

Original language	English
Title of host publication	2018 IEEE Custom Integrated Circuits Conference, CICC 2018
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1-4
Number of pages	4
ISBN (Electronic)	9781538624838
DOIs	https://doi.org/10.1109/CICC.2018.8357047
State	Published - 9 May 2018
Event	2018 IEEE Custom Integrated Circuits Conference, CICC 2018 - San Diego, United States Duration: 8 Apr 2018 → 11 Apr 2018

Publication series

Name	2018 IEEE Custom Integrated Circuits Conference, CICC 2018

Conference

Conference	2018 IEEE Custom Integrated Circuits Conference, CICC 2018
Country/Territory	United States
City	San Diego
Period	8/04/18 → 11/04/18

Keywords

backscatter
low-power wireless
neuromodulation
peripheral nerve
Stimulation
ultrasound

Access to Document

10.1109/CICC.2018.8357047

Cite this

Johnson, B. C., Shen, K., Piech, D., Ghanbari, M. M., Li, K. Y., Neely, R., Carmena, J. M., Maharbiz, M. M., & Muller, R. (2018). StimDust: A 6.5mm³, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency. In 2018 IEEE Custom Integrated Circuits Conference, CICC 2018 (pp. 1-4). (2018 IEEE Custom Integrated Circuits Conference, CICC 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CICC.2018.8357047

@inproceedings{ae35a6a32d60461aa4f803bec95deff2,

title = "StimDust: A 6.5mm3, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency",

abstract = "We present a 6.5mm3, 10mg, wireless peripheral nerve stimulator. The stimulator is powered and controlled through ultrasound from an external transducer and utilizes a single 750×750×750μm3 piezocrystal for downlink communication, powering, and readout, reducing implant volume and mass. An IC with 0.06mm2 active circuit area, designed in TSMC 65nm LPCMOS process, converts harvested ultrasound to stimulation charge with a peak efficiency of 82%. A custom wireless protocol that does not require a clock or memory circuits reduces on-chip power to 4μW when not stimulating. The encapsulated stimulator was cuffed to the sciatic nerve of an anesthetized rodent and demonstrated full-scale nerve activation in vivo. We achieve a highly efficient and temporally precise wireless peripheral nerve stimulator that is the smallest and lightest to our knowledge.",

keywords = "backscatter, low-power wireless, neuromodulation, peripheral nerve, Stimulation, ultrasound",

author = "Johnson, {Benjamin C.} and Konlin Shen and David Piech and Ghanbari, {M. Meraj} and Li, {Ka Yiu} and Ryan Neely and Carmena, {Jose M.} and Maharbiz, {Michel M.} and Rikky Muller",

note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 2018 IEEE Custom Integrated Circuits Conference, CICC 2018 ; Conference date: 08-04-2018 Through 11-04-2018",

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language = "English",

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Johnson, BC, Shen, K, Piech, D, Ghanbari, MM, Li, KY, Neely, R, Carmena, JM, Maharbiz, MM & Muller, R 2018, StimDust: A 6.5mm³, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency. in 2018 IEEE Custom Integrated Circuits Conference, CICC 2018. 2018 IEEE Custom Integrated Circuits Conference, CICC 2018, Institute of Electrical and Electronics Engineers Inc., pp. 1-4, 2018 IEEE Custom Integrated Circuits Conference, CICC 2018, San Diego, United States, 8/04/18. https://doi.org/10.1109/CICC.2018.8357047

StimDust: A 6.5mm³, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency. / Johnson, Benjamin C.; Shen, Konlin; Piech, David et al.
2018 IEEE Custom Integrated Circuits Conference, CICC 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 1-4 (2018 IEEE Custom Integrated Circuits Conference, CICC 2018).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - We present a 6.5mm3, 10mg, wireless peripheral nerve stimulator. The stimulator is powered and controlled through ultrasound from an external transducer and utilizes a single 750×750×750μm3 piezocrystal for downlink communication, powering, and readout, reducing implant volume and mass. An IC with 0.06mm2 active circuit area, designed in TSMC 65nm LPCMOS process, converts harvested ultrasound to stimulation charge with a peak efficiency of 82%. A custom wireless protocol that does not require a clock or memory circuits reduces on-chip power to 4μW when not stimulating. The encapsulated stimulator was cuffed to the sciatic nerve of an anesthetized rodent and demonstrated full-scale nerve activation in vivo. We achieve a highly efficient and temporally precise wireless peripheral nerve stimulator that is the smallest and lightest to our knowledge.

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Johnson BC, Shen K, Piech D, Ghanbari MM, Li KY, Neely R et al. StimDust: A 6.5mm³, wireless ultrasonic peripheral nerve stimulator with 82% peak chip efficiency. In 2018 IEEE Custom Integrated Circuits Conference, CICC 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 1-4. (2018 IEEE Custom Integrated Circuits Conference, CICC 2018). doi: 10.1109/CICC.2018.8357047