Synthesis and stabilization of colloidal gold nanoparticle suspensions for SERS

Paul H. Davis, Cody P. Morrisey, Sean M.V. Tuley, Chris I. Bingham

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

6 Scopus citations

Abstract

Colloidal gold nanoparticles were synthesized by thiosulfate reduction of aqueous HAuCl4. Nanoparticle flocculation was controlled by addition of a stabilizing agent (e.g., Na2SO4 or NaCl) 5 minutes into the reaction. Synthesis kinetics were followed by monitoring the growth in intensity of the surface plasmon resonance (SPR) at ~535 nm using visible-NIR absorption spectroscopy. In addition to the SPR, the time- dependent spectra also exhibited an extended plasmon band (EPB) in the NIR that initially increased in intensity and red- shifted with time before blue-shifting and eventually disappearing due to changes in nanoparticle flocculation. TEM and x-ray diffraction measurements showed that the resultant nanoparticles were predominantly spherical in shape and ~20-30 nm in diameter. Surface chemistry was confirmed using XPS. The stabilizing agent was found to play a key role in the subsequent SERS activity of the nanoparticles by adsorbing to their surface, preventing premature nanoparticle aggregation and mediating the analyte-nanoparticle interaction.

Original languageEnglish
Title of host publicationNanoparticles
Subtitle of host publicationSynthesis, Stabilization, Passivation, and Functionalization
PublisherAmerican Chemical Society
Pages16-30
Number of pages15
ISBN (Print)9780841269699
DOIs
StatePublished - 19 Sep 2008
Externally publishedYes

Publication series

NameACS Symposium Series
Volume996
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

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