TY - JOUR
T1 - The Effect of Early-Life Seizures on Cognitive and Motor Development
T2 - A Case Series
AU - Jensen-Willett, Sandra
AU - Cunha, Andrea
AU - Lobo, Michele A.
AU - Harbourne, Regina
AU - Dusing, Stacey C.
AU - McCoy, Sarah W.
AU - Koziol, Natalie A.
AU - Hsu, Lin Ya
AU - Marcinowski, Emily C.
AU - Babik, Iryna
AU - An, Mihee
AU - Bovaird, James A.
N1 - Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.
PY - 2022/7/1
Y1 - 2022/7/1
N2 - Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.
AB - Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled trial. Seven received 3 months of twice weekly START-Play intervention; 6 continued with usual care early intervention. Bayley Scales of Infant Development-III (Cognitive Composite), Gross Motor Function Measure-66 Item Set, Assessment of Problem-Solving in Play, and reaching assessments were administered at baseline, 3, 6, and 12 months postbaseline. Change scores are reported at 3 and 12 months postbaseline. Results: Over time, plateau or decline was noted in standardized cognition measures; motor development improved or was stable. Children receiving START-Play showed positive trends in problem-solving (71.4%) and reaching behaviors (57.2%). Conclusions: Interventions such as START-Play that combine motor and cognitive constructs may benefit children with early-life seizures.
KW - development
KW - early intervention
KW - seizures
UR - http://www.scopus.com/inward/record.url?scp=85134083551&partnerID=8YFLogxK
U2 - 10.1097/PEP.0000000000000918
DO - 10.1097/PEP.0000000000000918
M3 - Article
C2 - 35703307
AN - SCOPUS:85134083551
SN - 0898-5669
VL - 34
SP - 425
EP - 431
JO - Pediatric Physical Therapy
JF - Pediatric Physical Therapy
IS - 3
ER -