TY - JOUR
T1 - Unzipping and shearing DNA with electrophoresed nanoparticles in hydrogels
AU - Cervantes-Salguero, Keitel
AU - Kawamata, Ibuki
AU - Nomura, Shin Ichiro M.
AU - Murata, Satoshi
N1 - Publisher Copyright:
© the Owner Societies 2017.
PY - 2017
Y1 - 2017
N2 - We show electric control of unzipping and shearing dehybridization of a DNA duplex anchored to a hydrogel. Tensile force is applied by electrophoresing (25 V cm-1) gold nanoparticles pulling the DNA duplex. The pulled DNA strand is gradually released from the hydrogel. The unzipping release rate is faster than shearing; for example, 3-fold for a 15 base pair duplex, which helps to design electrically driven DNA devices.
AB - We show electric control of unzipping and shearing dehybridization of a DNA duplex anchored to a hydrogel. Tensile force is applied by electrophoresing (25 V cm-1) gold nanoparticles pulling the DNA duplex. The pulled DNA strand is gradually released from the hydrogel. The unzipping release rate is faster than shearing; for example, 3-fold for a 15 base pair duplex, which helps to design electrically driven DNA devices.
UR - http://www.scopus.com/inward/record.url?scp=85024091272&partnerID=8YFLogxK
U2 - 10.1039/c7cp02214j
DO - 10.1039/c7cp02214j
M3 - Article
C2 - 28513698
AN - SCOPUS:85024091272
SN - 1463-9076
VL - 19
SP - 13414
EP - 13418
JO - Physical Chemistry Chemical Physics
JF - Physical Chemistry Chemical Physics
IS - 21
ER -