Using Cholera Toxin Chimera for Staphylococcus aureus Vaccine

Annie Walgren, Juliette Tinker

Research output: Contribution to conferencePresentation

Abstract

S. aureus is the primary cause of mastitis in cows. Mastitis is an infection of the mammary gland in the udder, which can be devastating for the animal and milk production. It is the most economically significant disease in the dairy industry. Creating a vaccine for S. aureus in dairy animals could reduce the number of antibiotics administered and prevent millions in economic losses annually. Cholera toxin can be used as an effective vaccine by replacing its toxic subunit with S. aureus antigens. This vaccine has the potential to induce antigen-specific immune responses that prevent the establishment of infection and mastitis development.

Original languageAmerican English
StatePublished - 12 Jul 2022

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