Using DNA to assemble and power the nanoworld

Research output: Contribution to journalConference articlepeer-review

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Abstract

The hybridization specificity of DNA allows the design of sets of oligomers which, when mixed together, self-assemble into complex nanoscale structures. Such structures can be induced to undergo configuration changes by incorporating motor domains consisting of regions of single-stranded DNA to which complementary "fuel" strands can hybridize. The principles of operation of these devices and prospects for making free-running DNA-based molecular motors are described. Potential applications for these devices, including the construction of materials whose mechanical properties can be altered in the response to the presence of specific oligomers, will be described.

Original languageEnglish
Article number09
Pages (from-to)82-90
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5592
DOIs
StatePublished - 2005
Externally publishedYes
EventNanofabrication: Technologies, Devices, and Applications - Philadelphia, PA, United States
Duration: 25 Oct 200428 Oct 2004

Keywords

  • DNA-based nanostructures
  • DNA-crosslinked gels
  • Molecular motors
  • Self-assembly

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