Abstract
DNA hybridization has been used to power a number of DNA-based nanostructures constructed out of DNA. Here some considerations that go into DNA-based motor design are briefly reviewed. The emphasis will be on the operation of toeholds, single-stranded sections of DNA that facilitate the process of strand removal during certain points in the operation of a DNA-based motor. Reaction kinetics measurements for toehold mediated strand exchange are reported. These measurements have served as a guide for choosing toehold lengths.
Original language | English |
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Pages (from-to) | 111-122 |
Number of pages | 12 |
Journal | Genetic Programming and Evolvable Machines |
Volume | 4 |
Issue number | 2 |
DOIs | |
State | Published - Jun 2003 |
Externally published | Yes |
Keywords
- DNA nanostructures
- Molecular motors
- Reaction kinetics
- Strand exchange
- Toeholds