Using DNA to power nanostructures

Bernard Yurke, Allen P. Mills

Research output: Contribution to journalArticlepeer-review

276 Scopus citations

Abstract

DNA hybridization has been used to power a number of DNA-based nanostructures constructed out of DNA. Here some considerations that go into DNA-based motor design are briefly reviewed. The emphasis will be on the operation of toeholds, single-stranded sections of DNA that facilitate the process of strand removal during certain points in the operation of a DNA-based motor. Reaction kinetics measurements for toehold mediated strand exchange are reported. These measurements have served as a guide for choosing toehold lengths.

Original languageEnglish
Pages (from-to)111-122
Number of pages12
JournalGenetic Programming and Evolvable Machines
Volume4
Issue number2
DOIs
StatePublished - Jun 2003
Externally publishedYes

Keywords

  • DNA nanostructures
  • Molecular motors
  • Reaction kinetics
  • Strand exchange
  • Toeholds

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