Abstract
DNA hybridization has been used to power a number of DNA-based nanostructures constructed out of DNA. Here some considerations that go into DNA-based motor design are briefly reviewed. The emphasis will be on the operation of toeholds, single-stranded sections of DNA that facilitate the process of strand removal during certain points in the operation of a DNA-based motor. Reaction kinetics measurements for toehold mediated strand exchange are reported. These measurements have served as a guide for choosing toehold lengths.
| Original language | English |
|---|---|
| Pages (from-to) | 111-122 |
| Number of pages | 12 |
| Journal | Genetic Programming and Evolvable Machines |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 2003 |
| Externally published | Yes |
Keywords
- DNA nanostructures
- Molecular motors
- Reaction kinetics
- Strand exchange
- Toeholds